HCID 54186826, compound → HCID 14556350, compound

Participants

Reaction Steps

0.01 mole of 3-methyl-6-{3-[4-(4-fluorophenyl)-1-piperazinyl]-1-propenyl}benzoxazolinone is dissolved in ethyl acetate in a 500-cm3 flask equipped with a three-way tap and a magnetic stirrer, and 0.5 g of Raney nickel is then added. The mixture is stirred under a hydrogen atmosphere at room temperature and atmospheric pressure. After the theoretical amount of hydrogen has been absorbed, the reaction medium is filtered and the filtrate is evaporated to dryness on a water bath under vacuum. The residue is crystallized in ethanol.

Provenance & Evidence