Sulfuric Acid → HCID 14836216, compound

HRID 1087757Notes

Reaction equation

HRID 1087757 reaction equation
[CH2:1]([NH:5][C:6]([NH:8][CH2:9][CH2:10][CH3:11])=[O:7])[CH2:2][CH2:3][CH3:4].[CH:12]([CH:14]=[O:15])=[O:13].S(=O)(=O)(O)O>C(O)(C)C>[CH:2]([O:13][CH:12]1[CH:14]([O:15][CH:10]([CH3:11])[CH3:9])[N:5]([CH2:1][CH2:2][CH2:3][CH3:4])[C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH3:11])([CH3:3])[CH3:1]

Participants

5

Reactant 3

HCID 1118Sulfuric AcidHCID 7860GlyoxalHCID 14836212N-Butyl-N'-propylurea

Product 1

HCID 14836216HCID 14836216, compoundYield 33%

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Example 11 was repeated with 4.21 g of 1-butyl-3-propylurea, 4 ml of 40% aqueous glyoxal, 80 ml of isopropyl alcohol and 1 ml of conc. sulfuric acid. After work up and silica gel chromatography gave 2.6 g (33%) of an oil.

Sources & evidence

ORD record
ord-c916d1d36750472789b85f7abe036d5b
Source dataset
uspto-grants-1990_10
Patent number
US04960771

Reaction notes

Loading…