HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrazole → 2-Methyl-2-(pyrazol-1-yl)-butan-3one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrazole | HCID 1048 | — |
| Reactant | 3-Bromo-3-methyl-2-butanone | HCID 344911 | — |
| Product | 2-Methyl-2-(pyrazol-1-yl)-butan-3one | HCID 14369944 | 70% |
Reaction Steps
1 mol of methyl bromoisopropyl ketone is added dropwise at 100° C. to a melt of 4 mols of pyrazole. The reaction mixture is stirred for a further hour. Following customary working up, 2-methyl-2-(pyrazol-1-yl)-butan-3one is obtained in a yield of 70%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04960781 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-a7d1187f40a046bca1ab0878b8c227ad |
| Source note | uspto-grants-1990_10 |