HCID 22163920, compound → HCID 22163922, compound

HRID 1087799Notes

Reaction equation

HRID 1087799 reaction equation
[CH3:1][NH:2][C:3]([N:5]([CH:14]([C:16]1[CH:20]=[CH:19][N:18]([C:21]2[C:26]([CH3:27])=[CH:25][CH:24]=[CH:23][C:22]=2[CH3:28])[CH:17]=1)[CH3:15])[O:6]CC1C=CC=CC=1)=[O:4]>C(OCC)(=O)C>[CH3:1][NH:2][C:3]([N:5]([CH:14]([C:16]1[CH:20]=[CH:19][N:18]([C:21]2[C:26]([CH3:27])=[CH:25][CH:24]=[CH:23][C:22]=2[CH3:28])[CH:17]=1)[CH3:15])[OH:6])=[O:4]

Participants

3

Reactant 1

HCID 22163920HCID 22163920, compound

Product 1

HCID 22163922HCID 22163922, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A solution of 1.0 g of N-(N'-methylcarbamoyl)-N-benzyloxy-1-[1-(2,6-dimethylphenyl)-1H-pyrrol-3-yl]-ethylamine in 50 ml of ethyl acetate is hydrogenated at room temperature and 3 atmospheres pressure for 3 hours to yield N-(N'-methylcarbamoyl)-N-hydroxy-1-[1-(2,6-dimethylphenyl)-1H-pyrrol-3-yl]-ethylamine.

Workup

  1. customis hydrogenated at room temperature

Sources & evidence

ORD record
ord-53e7307b009d4e72a86511b51c1ef270
Source dataset
uspto-grants-1990_10
Patent number
US04960787

Reaction notes

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