1-(2-Methoxyphenyl)piperazine → HCID 14763470, compound

Participants

Reaction Steps

This compound was prepared according to the procedure used to synthesize the compound of Example 11. A mixture of 4.9 g (0.03 mole) of 1,1'-carbonydiimidazole, 2.6 g (0.03 mole) of unsym-dimethylethylenediamine and 5.8 g (0.03 mole) of 1-(2-methoxyphenyl)piperazine in a total volume of 200 ml of tetrahydrofuran gave an oil which solidified. After trituration with petroleum ether (30°-60° C.), the collected solid was recrystallized from benzene-petroleum ether to yield 4.5 g (49%) of the title compound as an off-white solid, m.p. 98°-100° C.

Provenance & Evidence