HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Dimethylethylenediamine → HCID 14763483, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Dimethylethylenediamine | HCID 66053 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 1-(4-Nitrophenyl)piperazine | HCID 80447 | — |
| Reactant | N-[2-(Dimethylamino)ethyl]-4-(4-fluorophenyl)-1-piperazinecarboxamide | HCID 14763463 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 14763483 | HCID 14763483 | 54% |
Reaction Steps
This compound was prepared according to the procedure used to synthesize the compound of Example 11. A mixture of 5.5 g (0.03 mole) of 1,1'-carbonyldiimidazole, 3.0 g (0.03 mole) of unsym-dimethylethylenediamine and 7.0 g (0.03 mole) of 1-(4-nitrophenyl)piperazine in a total volume of 200 ml of tetrahydrofuran gave an oil that solidified. The solid was recrystallized from benzene to give 5.8 g (54%) of the title compound as a yellow solid, m.p. 115°-120° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04960776 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-f88a0d313d0c41c9870225be9179ce23 |
| Source note | uspto-grants-1990_10 |