HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 22163781, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | N,N-Dimethylethylenediamine | HCID 66053 | — |
| Reactant | 1-(3-Fluorophenyl)piperazine | HCID 77418 | — |
| Reactant | N-[2-(Dimethylamino)ethyl]-4-(4-fluorophenyl)-1-piperazinecarboxamide | HCID 14763463 | — |
| Product | HCID 22163781 | HCID 22163781 | — |
Reaction Steps
This compound was prepared according to the procedure used to synthesize the compound of Example 11. A mixture of 2.4 g (0.015 mole) of 1-(3-fluorophenyl)piperazine and 1.3 g (0.015 mole) of unsym-dimethyethylenediamine in a total volume of 200 ml of tetrahydrofuran gave a clear oil as residue. The hydrochloride was formed in ethereal hydrogen chloride and the collected solid was recrystallized from methanol-ethyl ether to give 2.7 g (50%) of the title compound as a white solid, m.p. 200°-203° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04960776 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-5db03516df8b4f74ba06df9c8a637ab5 |
| Source note | uspto-grants-1990_10 |