HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Dimethylethylenediamine → HCID 14763478, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Dimethylethylenediamine | HCID 66053 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 4-(1-Piperazinyl)benzamide | HCID 11106509 | — |
| Reactant | N-[2-(Dimethylamino)ethyl]-4-(4-fluorophenyl)-1-piperazinecarboxamide | HCID 14763463 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 14763478 | HCID 14763478 | 20% |
Reaction Steps
This compound was prepared according to the procedure used to synthesize the compound of Example 11. A mixture of 3.1 g (0.019 mole) of 1,1'-carbonyldiimidazole, 1.7 g (0.019 mole) of unsym-dimethylethylenediamine and 3.9 g (0.019 mole) of 4-(1-piperazinyl)benzamide in a total volume of 150 ml of tetrahydrofuran gave a suspended white solid. The collected solid was recrystallized from ethanol-benzene to give 1.2 g (20%) of the title compound as a white solid, m.p. 193°-195° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04960776 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-0424fb231a064f75b2d0ab0755934c9c |
| Source note | uspto-grants-1990_10 |