Isopropylamine → HCID 70358954, compound

HRID 1087930Notes

Reaction equation

HRID 1087930 reaction equation
[CH3:1][NH:2][S:3]([C:6]1(Cl)[NH:10][C:9]([Cl:11])=[CH:8][S:7]1)(=[O:5])=[O:4].[CH:13]([NH2:16])([CH3:15])[CH3:14]>C1(C)C=CC=CC=1>[CH3:1][N:2]([NH:16][CH:13]([CH3:15])[CH3:14])[S:3]([C:6]1[S:7][CH:8]=[C:9]([Cl:11])[N:10]=1)(=[O:5])=[O:4]

Participants

4

Reactant 2

HCID 6363IsopropylamineHCID 22164323HCID 22164323, compound

Product 1

HCID 70358954HCID 70358954, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

In analogy to Example 5, the N-methyl-2-N-isopropylamino-4-chlorothiazole-sulphonamide was prepared by reacting N-methyl-2,4-dichlorothiazole-sulphomamide from Example 2 with a 65% strength aqueous isopropylamine solution. Following recrystallization from toluene, 89% yield of product of m.p. 135° C. were obtained.

Sources & evidence

ORD record
ord-4b037f4d6b7a4d51b3a8184c5525fc45
Source dataset
uspto-grants-1990_10
Patent number
US04960899

Reaction notes

Loading…