Neopentylamine → HCID 70358946, compound

HRID 1087933Notes

Reaction equation

HRID 1087933 reaction equation
Cl[C:2]1([S:8](Cl)(=[O:10])=[O:9])[NH:6][C:5]([Cl:7])=[CH:4][S:3]1.[CH3:12][C:13]([CH3:17])([CH3:16])[CH2:14][NH2:15]>>[CH3:12][C:13]([CH3:17])([CH3:16])[CH2:14][N:15]([NH:15][CH2:14][C:13]([CH3:17])([CH3:16])[CH3:12])[S:8]([C:2]1[S:3][CH:4]=[C:5]([Cl:7])[N:6]=1)(=[O:10])=[O:9]

Participants

3

Reactant 2

HCID 79882NeopentylamineHCID 22164315HCID 22164315, compound

Product 1

HCID 70358946HCID 70358946, compoundYield 67%

Procedure

In analogy to Example 13, the N-(2,2-dimethylpropyl)-2-N-(2, 2-dimethyl-propylamino)-4-chlorothiazolesulphonamide was prepared by reacting 2,4-dichlorothiazolesulphonyl chloride from Example 1 with 2,2-dimethylpropylamine. Following recrystallization from toluene, the product of m.p. 157° C. was obtained in 67% yield.

Workup

  1. customrecrystallization from toluene
  2. customthe product of m.p. 157° C. was obtained in 67% yield

Sources & evidence

ORD record
ord-3204e7898ebe4e219c6d07c27be4e9c9
Source dataset
uspto-grants-1990_10
Patent number
US04960899

Reaction notes

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