Methylamine → HCID 15598737, compound

HRID 1087965Notes

Reaction equation

HRID 1087965 reaction equation
[OH:1][C:2]1[CH:25]=[CH:24][C:5]([C:6]2[C:15](=[O:16])[C:14]3[C:9](=[CH:10][C:11]([OH:18])=[CH:12][C:13]=3[OH:17])[O:8][C:7]=2[C:19](OCC)=[O:20])=[CH:4][CH:3]=1.[CH3:26][NH2:27]>>[OH:1][C:2]1[CH:25]=[CH:24][C:5]([C:6]2[C:15](=[O:16])[C:14]3[C:9](=[CH:10][C:11]([OH:18])=[CH:12][C:13]=3[OH:17])[O:8][C:7]=2[C:19]([NH:27][CH3:26])=[O:20])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 6329MethylamineHCID 14459364HCID 14459364, compound

Product 1

HCID 15598737HCID 15598737, compound

Procedure

A mixture of ethyl 4',5,7-trihydroxy-2-isoflavonecarboxylate (100 mg) and 30% methanolic solution of methylamine (5 ml) was stirred at room temperature for 30 minutes, the solvent was distilled off under reduced pressure, and the solid residue was recrystallized from methanol, affording 50 mg of 4',5,7-trihydroxy-N-methyl-2-isoflavonecarboxamide.

Workup

  1. distillationthe solvent was distilled off under reduced pressure
  2. customthe solid residue was recrystallized from methanol

Sources & evidence

ORD record
ord-21aa3ad7205b4c28b000c0502d84d990
Source dataset
uspto-grants-1990_10
Patent number
US04960908

Reaction notes

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