Water → HCID 14324491, compound

Participants

Reaction Steps

1.0 kg of ethyl pivaloylacetate was dissolved in 2.5 liters of ethanol and 320 g of hydrazine hydrate was dropwise added thereto with cooling with water. After the completion of the dropwise addition, the whole was reacted overnight at room temperature, and then 5.0 liters of water was added thereto and stirred. The crystal which precipitated was filtered under reduced pressure, washed well with water and then with a small amount of methanol, and then dried with air. Yield: 812 g, 98.5%.

Provenance & Evidence