反应详情

1.0 kg of ethyl pivaloylacetate was dissolved in 2.5 liters of ethanol and 320 g of hydrazine hydrate was dropwise added thereto with cooling with water. After the completion of the dropwise addition, the whole was reacted overnight at room temperature, and then 5.0 liters of water was added thereto and stirred. The crystal which precipitated was filtered under reduced pressure, washed well with water and then with a small amount of methanol, and then dried with air. Yield: 812 g, 98.5%.

1. additionAfter the completion of the dropwise addition
2. customthe whole was reacted overnight at room temperature
3. customThe crystal which precipitated
4. filtrationwas filtered under reduced pressure
5. washwashed well with water
6. dry with materialwith a small amount of methanol, and then dried with air