HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-3-methylphenol → 1-Chloro-4-methoxy-2-methylbenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-3-methylphenol | HCID 1732 | — |
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 1-Chloro-4-methoxy-2-methylbenzene | HCID 458156 | — |
Reaction Steps
A solution of 3-methyl-4-chlorophenol (100 g), methyl iodide (200 g) and K2CO3 (150 g) in acetone (500 ml) were refluxed 6 hours, filtered and evaporated to yield the title compound which was used as is in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04962203 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-d2d2cf33358544cfae3594051f433059 |
| Source note | uspto-grants-1990_10 |