Sodium Hydroxide → 4-(3-(2-(7-Bromoquinolin-2-yl)ethenyl)phenoxy)butyric acid sodium salt

Participants

Reaction Steps

To a solution of the ester of Example 5, Step 2, (15 g) in ethanol (200 ml) and tetrahydrofuran (200 ml) was added 2N NaOH (35 ml). The reaction was stirred at room temperature overnight and the product filtered The solid was stirred for 2 hours at room temperature in ethanol (100 ml) and filtered to give the title compound.

Provenance & Evidence