反应详情

A solution of the phenol from Step 3 (470 mg), methyl ethyl ketone (10 mL), milled potassium carbonate (600 mg) and ethyl 4-iodo-butyrate (421 mg) was refluxed overnight The solids were filtered, and the filtrate was evaporated. The residue was purified by flash chromatography using toluene-ethyl acetate (10:0.3) to afford the title product as yellow solid: m.p. 61°-63° C.

1. temperaturewas refluxed overnight The solids
2. filtrationwere filtered
3. customthe filtrate was evaporated
4. customThe residue was purified by flash chromatography