反应详情

A mixture of 220 g 7-bromoquinaldine, 180 g N-bromosuccinimide and 1 g dibenzoylperoxide in CCl4 (1 L) was illuminated with a 275 W sun lamp at reflux for 12 hours. The reaction mixture was cooled and directly chromatographed on 2 kg silica gel. Elution with toluene afforded the title compound which was used as is for the next step.

1. customwas illuminated with a 275 W sun lamp
2. temperatureat reflux for 12 hours
3. temperatureThe reaction mixture was cooled
4. customdirectly chromatographed on 2 kg silica gel
5. washElution with toluene