HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → (7-Bromo-quinolin-2-yl)methylbromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 7-Bromo-2-methylquinoline | HCID 12332896 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | (7-Bromo-quinolin-2-yl)methylbromide | HCID 22163097 | — |
Reaction Steps
A mixture of 220 g 7-bromoquinaldine, 180 g N-bromosuccinimide and 1 g dibenzoylperoxide in CCl4 (1 L) was illuminated with a 275 W sun lamp at reflux for 12 hours. The reaction mixture was cooled and directly chromatographed on 2 kg silica gel. Elution with toluene afforded the title compound which was used as is for the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04962203 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-ca978d4c001a4ffc80af50722d6f7f92 |
| Source note | uspto-grants-1990_10 |