Sodium Hydroxide → HCID 22163105, compound

Participants

Reaction Steps

A mixture of the ester (Step 3) (861 mg), methanol (13 mL) and 5N sodium hydroxide (0.54 mL) was heated under reflux for 2 hours. The reaction mixture was evaporated to approximately 4 mL and acidified to pH 4.5 with HCl (0.5N). This gave a gum which crystallized in methanol to give the title compound. mp 178°

Provenance & Evidence