Benzene → HCID 22163148, compound

HRID 1088507Notes

Reaction equation

HRID 1088507 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)(=O)[CH3:2].[CH2:10]([O:12][C:13](=[O:21])[C:14]1[CH:19]=[CH:18][C:17]([NH2:20])=[CH:16][CH:15]=1)[CH3:11].C1C=CC=CC=1>O>[CH3:2][C:1](=[N:20][C:17]1[CH:18]=[CH:19][C:14]([C:13]([O:12][CH2:10][CH3:11])=[O:21])=[CH:15][CH:16]=1)[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

Participants

5

Reactant 3

HCID 241BenzeneHCID 2337BenzocaineHCID 7410Acetophenone

Product 1

HCID 22163148HCID 22163148, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of acetophenone (44 ml), ethyl-p-aminobenzoate (60 g), benzene (100 ml) was refluxed in the presence of molecular sieve (100 g) with continuous removal of water. The crude product was purified by crystallizing it from ethanol to give N-(α-methyl benzylidene)-p-carbethoxy aniline (XI). XI had a m.p. of 87° C.

Workup

  1. customThe crude product was purified
  2. customby crystallizing it from ethanol

Sources & evidence

ORD record
ord-0874799887264143894086407acce689
Source dataset
uspto-grants-1990_10
Patent number
US04962234

Reaction notes

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