Benzene → HCID 22163151, compound

HRID 1088523Notes

Reaction equation

HRID 1088523 reaction equation
[CH2:1]1[CH2:11][C:9](=O)[C:8]2[C:3](=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH2:2]1.[CH2:12]([O:14][C:15](=[O:23])[C:16]1[CH:21]=[CH:20][C:19]([NH2:22])=[CH:18][CH:17]=1)[CH3:13].C1C=CC=CC=1>O>[C:9]1(=[N:22][C:19]2[CH:18]=[CH:17][C:16]([C:15]([O:14][CH2:12][CH3:13])=[O:23])=[CH:21][CH:20]=2)[C:8]2[C:3](=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH2:2][CH2:1][CH2:11]1

Participants

5

Reactant 3

HCID 241BenzeneHCID 2337BenzocaineHCID 107241-Tetralone

Product 1

HCID 22163151HCID 22163151, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of α-tetralone (40 ml), ethyl-p-amino-benzoate (42 g) and benzene (100 ml) was refluxed in the presence of molecular sieve (100 g) with the continuous removal of water. The crude product was crystallized from ethanol to give N-(1,2,3,4-tetrahydonaphthylidene)-p-carbethoxyaniline (XXVIII). XXVIII had a.m.p. of 108.5° C.

Workup

  1. customThe crude product was crystallized from ethanol

Sources & evidence

ORD record
ord-a1e83c5405a94189936c93b85832b6af
Source dataset
uspto-grants-1990_10
Patent number
US04962234

Reaction notes

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