Acetone → HCID 15052152, compound

HRID 1088555Notes

Reaction equation

HRID 1088555 reaction equation
[N:1]12[CH2:8]CC([CH2:5][CH2:6]1)[CH2:3][CH:2]2O.[C:10]1([CH3:21])[CH:15]=[CH:14][C:13]([S:16]([O:19]C)(=[O:18])=[O:17])=[CH:12][CH:11]=1.[CH3:22][C:23]([CH3:25])=[O:24]>>[C:10]1([CH3:21])[CH:11]=[CH:12][C:13]([S:16]([O-:19])(=[O:17])=[O:18])=[CH:14][CH:15]=1.[CH3:8][N+:1]12[CH2:6][CH2:5][CH:25]([CH2:3][CH2:2]1)[CH:23]([OH:24])[CH2:22]2

Participants

4

Reactant 3

HCID 180AcetoneHCID 6645Methyl p-toluenesulfonateHCID 14389216HCID 14389216, compound

Product 1

HCID 15052152HCID 15052152, compound

Procedure

In 10 ml of acetone was dissolved 1.27 g of quinuclidinol, and 1.86 g of methyl p-toluenesulfonate was added dropwise to the resulting solution. The mixture was stirred at room temperature, heated under reflux, and cooled to precipitate crystals. The crystals were collected by filtration and dried to give 2.81 g of the desired product.

Workup

  1. additionwas added dropwise to the resulting solution
  2. temperatureheated
  3. temperatureunder reflux
  4. temperaturecooled
  5. customto precipitate crystals
  6. filtrationThe crystals were collected by filtration
  7. customdried

Sources & evidence

ORD record
ord-476c9ac92cf94798bc6edc4f328b305c
Source dataset
uspto-grants-1990_10
Patent number
US04962096

Reaction notes

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