反应详情

In 12 ml of acetone was dissolved 887 mg of 2-methyl-1,2,3,4-tetrahydro-3-isoquinolinemethanol, and 932 mg of methyl p-toluenesulfonate was added dropwise to the resulting solution. The mixture was stirred at room temperature for 3 hours to precipitate crystals. The crystals were collected by filtration, washed with acetone and dried under reduced pressure to give 1.31 g of the desired compound.

1. additionwas added dropwise to the resulting solution
2. customto precipitate crystals
3. filtrationThe crystals were collected by filtration
4. washwashed with acetone
5. customdried under reduced pressure