Methyl p-toluenesulfonate → HCID 15052253, compound

HRID 1088568Notes

Reaction equation

HRID 1088568 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][CH:5]=[C:4]([CH2:8][OH:9])[CH2:3]1.[C:10]1([CH3:21])[CH:15]=[CH:14][C:13]([S:16]([O:19]C)(=[O:18])=[O:17])=[CH:12][CH:11]=1>>[C:10]1([CH3:21])[CH:11]=[CH:12][C:13]([S:16]([O-:19])(=[O:17])=[O:18])=[CH:14][CH:15]=1.[CH3:1][N+:2]1([CH3:10])[CH2:7][CH2:6][CH:5]=[C:4]([CH2:8][OH:9])[CH2:3]1

Participants

3

Reactant 2

HCID 6645Methyl p-toluenesulfonateHCID 4247001-Methyl-1,2,5,6-tetrahydropyridine-3-methanol

Product 1

HCID 15052253HCID 15052253, compoundYield 179.4%

Procedure

The procedures of Reference Example 10 were repeated using 2.8 g of 1-methyl-1,2,5,6-tetrahydro-3-pyridinemethanol and 4.1 g of methyl p-toluenesulfonate to give 6.19 g of the desired compound as a white crystalline product.

Sources & evidence

ORD record
ord-2adeffc98b5546d0b6232f55a0b87c61
Source dataset
uspto-grants-1990_10
Patent number
US04962096

Reaction notes

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