HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-[[(S)-2-amino-1-oxo-3-phenylpropyl]amino]propanoic acid, phenylmethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 3-[[(S)-2-amino-1-oxo-3-phenylpropyl]amino]propanoic acid, phenylmethyl ester, hydrochloride | HCID 69462227 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3-[[(S)-2-amino-1-oxo-3-phenylpropyl]amino]propanoic acid, phenylmethyl ester | HCID 14054165 | — |
Reaction Steps
The hydrochloride product from part (b) (1.81 g., 5 mmole) is partitioned between ethyl acetate and 5% sodium bicarbonate (200 ml. each). The organic layer is washed with brine, dried (MgSO4), and concentrated in vacuo to yield 3-[[(S)-2-amino-1-oxo-3-phenylpropyl]amino]propanoic acid, phenylmethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04963539 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-395c3d7d69694a91bcebbaddcf2387f7 |
| Source note | uspto-grants-1990_10 |