HCID 12228900, compound → 6(2H)-Isoquinolinone, octahydro-2-methyl-, cis-

HRID 1088643Notes

Reaction equation

HRID 1088643 reaction equation
[CH3:1][N:2]1[CH2:11][CH2:10][C:9]2[CH:4]([CH2:5][CH2:6][C:7](=[O:12])[CH:8]=2)[CH2:3]1>C(O)C.[Pd]>[CH3:1][N:2]1[CH2:11][CH2:10][C@H:9]2[C@H:4]([CH2:5][CH2:6][C:7](=[O:12])[CH2:8]2)[CH2:3]1

Participants

4

Reactant 1

HCID 12228900HCID 12228900, compound

Product 1

HCID 156639536(2H)-Isoquinolinone, octahydro-2-methyl-, cis-

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

2-Methyl-1,2,3,4,6,7,8,8a-octahydroisoquinol-6-one (3.30 g) in ethanol (75 ml) was hydrogenated at 60 p.s.i. in the presence of 5% Pd/C (0.5) for 2.5 hours. The catalyst was filtered off and the filtrate evaporated to give a light brown oil.

Workup

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate evaporated
  3. customto give a light brown oil

Sources & evidence

ORD record
ord-3f40ce1fce8b44ebaa08fc149962a8d9
Source dataset
uspto-grants-1990_10
Patent number
US04963558

Reaction notes

Loading…