4,4-Dipropyl-1,1-cyclohexanediacetic acid → HCID 14836346, compound

HRID 1088686Notes

Reaction equation

HRID 1088686 reaction equation
[CH2:1]([C:4]1([CH2:18][CH2:19][CH3:20])[CH2:9][CH2:8][C:7]([CH2:14][C:15]([OH:17])=[O:16])([CH2:10][C:11](O)=[O:12])[CH2:6][CH2:5]1)[CH2:2][CH3:3]>C(OC(=O)C)(=O)C>[CH2:18]([C:4]1([CH2:1][CH2:2][CH3:3])[CH2:5][CH2:6][C:7]2([CH2:10][C:11](=[O:12])[O:17][C:15](=[O:16])[CH2:14]2)[CH2:8][CH2:9]1)[CH2:19][CH3:20]

Participants

3

Reactant 1

HCID 148363454,4-Dipropyl-1,1-cyclohexanediacetic acid

Product 1

HCID 14836346HCID 14836346, compoundYield 90%

Reagents, catalysts & solvents 1

HCID 7918Acetic AnhydrideSolvent

Procedure

4,4-Dipropylcyclohexane-1,1 diacetic acid, prepared as described in Example 18, was dissolved in acetic anhydride and refluxed for 1-6h. The excess acetic anhydride was removed by distillation under reduced pressure and the residue was recrystallized form hexanes; m.p. 91-93° ; yield 90-95%.

Workup

  1. temperaturerefluxed for 1-6h
  2. customThe excess acetic anhydride was removed by distillation under reduced pressure
  3. customthe residue was recrystallized form hexanes

Sources & evidence

ORD record
ord-4f2dccf63d9845d4af61af7c75f86d83
Source dataset
uspto-grants-1990_10
Patent number
US04963557

Reaction notes

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