4-Phenylpiperidine → HCID 15101077, compound

HRID 1088765Notes

Reaction equation

[C:1]1([CH:7]2[CH2:12][CH2:11][NH:10][CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl[CH2:14][C:15]([N:17]1[CH2:22][CH:21]=[C:20]([C:23]2[CH:28]=[C:27]([Cl:29])[CH:26]=[CH:25][C:24]=2[Cl:30])[N:19]2[N:31]=[CH:32][C:33]([C:34]#[N:35])=[C:18]12)=[O:16]>>[Cl:30][C:24]1[CH:25]=[CH:26][C:27]([Cl:29])=[CH:28][C:23]=1[C:20]1[N:19]2[N:31]=[CH:32][C:33]([C:34]#[N:35])=[C:18]2[N:17]([C:15](=[O:16])[CH2:14][N:10]2[CH2:9][CH2:8][CH:7]([C:1]3[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=3)[CH2:12][CH2:11]2)[CH2:22][CH:21]=1

Participants

Reactant 2

HCID 698734-Phenylpiperidine

HCID 15101084HCID 15101084, compound

Product 1

HCID 15101077HCID 15101077, compound

Procedure

The above compound was prepared by the reaction of 4-phenylpiperidine with the compound of Example 9 by the method of Example 16, mp 199°-200° C.

Sources & evidence

ORD record: ord-816ff6c84b60468698d4a8f3740a13ae
Source dataset: uspto-grants-1990_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04963553

Reaction notes

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