Hydrochloric Acid → HCID 54080898, compound

HRID 1088865Notes

Reaction equation

HRID 1088865 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([C:12]#[N:13])[C:10]=1[OH:11])[C:5]([OH:7])=[O:6].Cl>C(O)CCC>[OH:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([C:12]#[N:13])[C:10]=1[OH:11])[C:5]([O:7][CH2:3][CH2:2][CH2:10][CH3:9])=[O:6]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 15173705HCID 15173705, compound

Product 1

HCID 54080898HCID 54080898, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Conditions

Temperature
100 °C

Procedure

A solution containing 0.5 g of 3,4-dihydroxy-5-cyanobenzoic acid in 10 ml of 1-butanol was saturated with gaseous hydrogen chloride at 0° C. The solution was then heated for 3 h at 100° C. The solvent was evaporated in vacuo and dichloromethane was added to the residue. The formed crystals were filtered. Yield 0.19 g (30%), m.p. 135°-140° C.

Workup

  1. customThe solvent was evaporated in vacuo and dichloromethane
  2. additionwas added to the residue
  3. filtrationThe formed crystals were filtered

Sources & evidence

ORD record
ord-266033fa18934c7497dbc0eca34d559c
Source dataset
uspto-grants-1990_10
Patent number
US04963590

Reaction notes

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