Hydrochloric Acid → HCID 19389213, compound

HRID 1088896Notes

Reaction equation

HRID 1088896 reaction equation
[CH2:1]([N:3]([CH2:18][CH3:19])[S:4]([C:7]1[CH:12]=[C:11]([Cl:13])[C:10](OC)=[C:9]([O:16]C)[CH:8]=1)(=[O:6])=[O:5])[CH3:2].B(Br)(Br)Br.[OH2:24].Cl>ClCCl>[CH2:1]([N:3]([CH2:18][CH3:19])[S:4]([C:7]1[CH:12]=[C:11]([Cl:13])[CH:10]=[C:9]([OH:16])[C:8]=1[OH:24])(=[O:6])=[O:5])[CH3:2]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 25134Boron tribromideHCID 19389186Benzenesulfonamide, 3-chloro-N,N-diethyl-4,5-dimethoxy-

Product 1

HCID 19389213HCID 19389213, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

To a solution containing 0.7 g of N,N-diethyl-5-chloro-3,4-dimethoxybenzenesulfonamide in 10 ml of dichloromethane 9.0 ml of 1 molar BBr3 in dichloromethane was added. The solution was stirred overnight at room temperature. Water and hydrochloric acid were added and the mixture was extracted with dichloromethane. The solvent was evaporated. Yield 0.3 g (47%), m.p. 62°-64° C.

Workup

  1. additionwas added
  2. extractionthe mixture was extracted with dichloromethane
  3. customThe solvent was evaporated

Sources & evidence

ORD record
ord-840c433bd2984b70b081251739a58dd3
Source dataset
uspto-grants-1990_10
Patent number
US04963590

Reaction notes

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