HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1089043Generated: October 25, 2026
Water → 5-Trifluoromethyl-4-chloro-3-(3'-dimethylhydrazino-4'-nitrophenoxy)-1-methylpyrazole
https://huagongshe.com/reaction/1089043
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Fluoro-2-(2,2-dimethylhydrazino) nitrobenzene | HCID 15017300 | — |
| Reactant | HCID 178481948 | HCID 178481948 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 5-Trifluoromethyl-4-chloro-3-(3'-dimethylhydrazino-4'-nitrophenoxy)-1-methylpyrazole | HCID 15017292 | 97.4% |
Reaction Steps
1.98 g (0.01 mol) of the product of step (a) was mixed with 2.2 g (0.011 mol) of 5-trifluoromethyl-4- chloro-3-hydroxy-1-methylpyrazole and 1.65 g of potassium carbonate in 15 ml of DMSO and heated for 24 hours at 90° C. The mixture was poured into 400 ml of H2O and extracted with ether. The organic layer was separated, washed with H2O, brine, dried over MgSO4 and solvent removed to give 3.7 g of solid, m.p. 72°-76° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04964895 |
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| Source dataset | uspto-grants-1990_10 |
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| ORD ID | ord-6e7acb2d51a14cae9c26ec836402a35f |
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| Source note | uspto-grants-1990_10 |
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