HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Acetylpyridine → (1R)-1-(pyridin-4-yl)ethan-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Acetylpyridine | HCID 9589 | — |
| Reactant | 4-Acetylpyridine | HCID 14282 | — |
| Product | (1R)-1-(pyridin-4-yl)ethan-1-ol | HCID 11804747 | — |
Reaction Steps
Example 1 was repeated except that 3-acetylpyridine used in Example 1 was replaced by 4-acetylpyridine to obtain (R)-1-(4-pyridyl)ethanol. [a]D25 =+32.4° (c=1.0, EtOH). Its optical purity was 99% ee or higher according to a high-speed liquid chromatography using an optical resolution column (CHIRAL CEL OB made by Daicel K. K.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04965018 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-2ae304ba4ce94eb5a19432e9cf616993 |
| Source note | uspto-grants-1990_10 |