Water → HCID 2790028, compound

HRID 1089098Notes

Reaction equation

HRID 1089098 reaction equation
[C:1]([CH2:4][N:5]1[C:9](=[O:10])[CH2:8][S:7][C:6]1=[S:11])([OH:3])=[O:2].[CH2:12]([N:14]([CH2:23][CH3:24])[C:15]1[CH:22]=[CH:21][C:18]([CH:19]=O)=[CH:17][CH:16]=1)[CH3:13].O>CN(C)C=O>[C:1]([CH2:4][N:5]1[C:9](=[O:10])[C:8](=[CH:19][C:18]2[CH:21]=[CH:22][C:15]([N:14]([CH2:12][CH3:13])[CH2:23][CH3:24])=[CH:16][CH:17]=2)[S:7][C:6]1=[S:11])([OH:3])=[O:2]

Participants

5

Reactant 3

HCID 962WaterHCID 671144-(Diethylamino)benzaldehydeHCID 797933-Thiazolidineacetic acid, 4-oxo-2-thioxo-

Product 1

HCID 2790028HCID 2790028, compoundYield 87%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
100 °C

Procedure

In 30 ml of dimethylformamide were dissolved 3.82 g of 3-carboxymethylrhodanine and 3.54 g of p-diethylaminobenzaldehyde, and the solution was stirred at 100° C. for 3 hours. After termination of the reaction, the solution was poured into water, and the formed precipitate was recovered by filtration, washed with water and recrystallized from acetone to obtain 3-carboxymethyl-5-(p-diethylaminobenzylidene)rhodanine (the yield was 87%).

Workup

  1. customAfter termination of the reaction
  2. filtrationthe formed precipitate was recovered by filtration
  3. washwashed with water
  4. customrecrystallized from acetone

Sources & evidence

ORD record
ord-9942c918a9a846beaf98e9b4956772a9
Source dataset
uspto-grants-1990_10
Patent number
US04965155

Reaction notes

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