Water → HCID 86744308, compound

HRID 1089134Notes

Reaction equation

HRID 1089134 reaction equation
[Cl:1][C:2]1[CH:15]=[C:14]([Cl:16])C=C[C:3]=1[C:4](=O)[CH2:5][C:6]1[NH:7][CH:8]=[CH:9][N:10]=1.[CH2:17]([NH2:26])[CH:18]=[CH:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.O.[C:28]1(C)C=CC=C[CH:29]=1>>[Cl:16][C:14]1[CH:15]=[C:2]([Cl:1])[CH:3]=[CH:4][C:5]=1[C:6]1[N:10]([CH2:28][CH:29]=[N:26][CH2:17][CH:18]=[CH:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:9]=[CH:8][N:7]=1

Participants

5

Reactant 4

HCID 962Water2×HCID 1140TolueneHCID 203693-Phenylprop-2-en-1-amineHCID 221427181-(2,4-dichlorophenyl)-2-(1H-imidazol-2-yl)ethanone

Product 1

HCID 86744308HCID 86744308, compound

Procedure

12.34 g (0.048 mol) of 2,4-dichlorophenacylimidazole and 6.66 g (0.05 mol) of cinnamylamine were suspended in 100 ml of toluene and the suspension was heated under reflux, using a water separator, until no further water of reaction was separated off. The solvent was removed in vacuo, after which 17.4 g (98% of theory) of a viscous oil were obtained.

Workup

  1. temperaturethe suspension was heated
  2. temperatureunder reflux
  3. customwas separated off
  4. customThe solvent was removed in vacuo
  5. customafter which 17.4 g (98% of theory) of a viscous oil were obtained

Sources & evidence

ORD record
ord-3b36f564aa4243c3847dff4e4017e7f0
Source dataset
uspto-grants-1990_10
Patent number
US04965277

Reaction notes

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