Diethylamine → N,N-diethyl-2-(2-thienyl)acetamide

HRID 1089189Notes

Reaction equation

[CH2:1]([N:3]([CH2:12][CH3:13])[C:4](=[O:11])[C:5]1C=[CH:9][CH:8]=[CH:7][CH:6]=1)[CH3:2].[S:14]1C=CC=C1CC(Cl)=O.C(NCC)C>>[CH2:1]([N:3]([CH2:12][CH3:13])[C:4](=[O:11])[CH2:5][C:6]1[S:14][CH:9]=[CH:8][CH:7]=1)[CH3:2]

Participants

Reactant 3

HCID 8021Diethylamine

HCID 15542N,N-Diethylbenzamide

HCID 1623622-Thiopheneacetyl chloride

Product 1

HCID 669955N,N-diethyl-2-(2-thienyl)acetamide

Procedure

The product of Example 42 was followed using 2-thiopheneacetyl chloride and diethylamine giving the desired product as an oil.

Sources & evidence

ORD record: ord-f28f473264984b169b56cc3e53ce9e69
Source dataset: uspto-grants-1990_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04965284

Reaction notes

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