Triethylamine → HCID 15713157, compound

HRID 1089328Notes

Reaction equation

HRID 1089328 reaction equation
[CH3:1][C:2]1([CH3:10])[NH:6][CH2:5][CH:4]([CH2:7][O:8][CH3:9])[O:3]1.[Br:11][CH:12]([CH2:16][Br:17])[C:13](Cl)=[O:14].C(N(CC)CC)C>C1C=CC=CC=1>[CH3:1][C:2]1([CH3:10])[N:6]([C:13](=[O:14])[CH:12]([Br:11])[CH2:16][Br:17])[CH2:5][CH:4]([CH2:7][O:8][CH3:9])[O:3]1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 867902,3-Dibromopropanoyl chlorideHCID 22160871HCID 22160871, compound

Product 1

HCID 15713157HCID 15713157, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

To 11.6 milliliters of 25 percent w/v, 2,2-dimethyl-5-methoxymethyl oxazolidine solution in 50 milliliters of benzene with 5.0 grams of 2,3-dibromopropionyl chloride was added dropwise 2.1 grams of triethylamine. After the reaction was complete the mixture was washed with water, separated, dried and the organic solvent removed in vacuo. There was obtained 2.7 grams of the title compound, nD30 1.4887. Analytical data supports the structure.

Workup

  1. washwas washed with water
  2. customseparated
  3. customdried
  4. customthe organic solvent removed in vacuo

Sources & evidence

ORD record
ord-4e8e29c3afa140969f51fdadd21ba618
Source dataset
uspto-grants-1990_10
Patent number
US04965368

Reaction notes

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