反应详情

First, 790 g of a solution of etidronic acid (158 g as etidronic acid) was heated to 70° C. and 461 g of a zinc oxide slurry (92.2 g as zinc oxide) held at 70° C. was added dropwise over about 30 minutes with constant stirring. The mol ratio of zinc oxide to etidronic acid was 1.5/1. This slurry was stirred at 60° to 70° C. for 4 hours, after which it was cooled to room temperature. The slurry was then filtered and the dehydrated cake was washed with distilled water 3 to 5 times. It was then filtered, dried and pulverized to give zinc etidronate.

1. customheld at 70° C.
2. additionwas added dropwise over about 30 minutes with constant stirring
3. filtrationThe slurry was then filtered
4. washthe dehydrated cake was washed with distilled water 3 to 5 times
5. filtrationIt was then filtered
6. customdried