HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 1-(3,5-Dichlorophenyl)-4-ethoxycarbonyl-5-pyrazolecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 1H-Pyrazole-4-carboxylic acid, 5-(aminocarbonyl)-1-(3,5-dichlorophenyl)- | HCID 163896 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 1-(3,5-Dichlorophenyl)-4-ethoxycarbonyl-5-pyrazolecarboxamide | HCID 14421312 | — |
Reaction Steps
Two g of the compound of Example 2 was suspended in 80 ml of absolute ethanol and hydrogen chloride 9as was bubbled through for 5 minutes. The mixture was then heated under reflux for 2 hours and cooled, and was then filtered. The solids were collected and dried to obtain 1.25 g of the desired product, m.p. 164°-166°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04966623 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-3c7f6434411a492c880df0fabf004958 |
| Source note | uspto-grants-1990_10 |