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HRID1089378

反应详情

EQUATION

反应方程式

HRID 1089378 的结构方程式

REACTANTS

反应物

2
结构：CCO
HCID702

Ethanol

C2H6O

结构：NC(=O)c1c(C(=O)O)cnn1-c1cc(Cl)cc(Cl)c1
HCID163896

1H-Pyrazole-4-carboxylic acid, 5-(aminocarbonyl)-1-(3,5-dichlorophenyl)-

C11H7Cl2N3O3

PRODUCTS

生成物

1
结构：CCOC(=O)c1cnn(-c2cc(Cl)cc(Cl)c2)c1C(N)=O
HCID14421312

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：Cl
溶剂HCID313

Hydrochloric Acid

ClH

PROCEDURE

实验过程

Two g of the compound of Example 2 was suspended in 80 ml of absolute ethanol and hydrogen chloride 9as was bubbled through for 5 minutes. The mixture was then heated under reflux for 2 hours and cooled, and was then filtered. The solids were collected and dried to obtain 1.25 g of the desired product, m.p. 164°-166°.

WORKUP

后处理

  1. customwas bubbled through for 5 minutes
  2. temperatureThe mixture was then heated
  3. temperatureunder reflux for 2 hours
  4. temperaturecooled
  5. filtrationwas then filtered
  6. customThe solids were collected
  7. customdried