3,4,5-Trimethoxyphenylacetaldehyde → HCID 14856374, compound

HRID 1089560Notes

Reaction equation

HRID 1089560 reaction equation
[O:1]1[C:9]2[CH:10]=[CH:11][C:12]([NH:14][S:15]([CH3:18])(=[O:17])=[O:16])=[CH:13][C:8]=2[O:7][CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[CH3:19][O:20][C:21]1[CH:22]=[C:23]([CH2:31][CH:32]=O)[CH:24]=[C:25]([O:29][CH3:30])[C:26]=1[O:27][CH3:28].[BH3-]C#N.[Na+]>>[CH3:30][O:29][C:25]1[CH:24]=[C:23]([CH2:31][CH2:32][N:4]2[CH2:3][CH2:2][O:1][C:9]3[CH:10]=[CH:11][C:12]([NH:14][S:15]([CH3:18])(=[O:17])=[O:16])=[CH:13][C:8]=3[O:7][CH2:6][CH2:5]2)[CH:22]=[C:21]([O:20][CH3:19])[C:26]=1[O:27][CH3:28]

Participants

4

Reactant 3

HCID 30143573,4,5-TrimethoxyphenylacetaldehydeHCID 5003444Sodium cyanoborohydrideHCID 14856361HCID 14856361, compound

Product 1

HCID 14856374HCID 14856374, compound

Procedure

In a manner similar to example 4, react N-(3,4,5,6-tetrahydro-2H-1,7,4-benzodioxazonin-9-yl)methanesulfonamide, 3,4,5-trimethoxybenzeneacetaldehyde, and NaBH3CN to obtain the title compound.

Sources & evidence

ORD record
ord-21d2b71c798c4f158541bd74af5ab490
Source dataset
uspto-grants-1990_10
Patent number
US04966967

Reaction notes

Loading…