Diethyl Ether → HCID 19915455, compound

HRID 1089626Notes

Reaction equation

HRID 1089626 reaction equation
Cl[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([C:11]([F:14])([F:13])[F:12])=[CH:4][C:3]=1[N+:15]([O-:17])=[O:16].C=C.[CH3:20][CH2:21][O:22][CH2:23]C.[OH-:25].[Na+]>O>[CH3:23][O:22][CH2:21][CH2:20][O:25][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([C:11]([F:14])([F:13])[F:12])=[CH:4][C:3]=1[N+:15]([O-:17])=[O:16]

Participants

6

Reactant 4

HCID 3283Diethyl EtherHCID 6325EthyleneHCID 98094-Chloro-3,5-dinitrobenzotrifluorideHCID 14798Sodium Hydroxide2×

Product 1

HCID 19915455HCID 19915455, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
60 °C

Procedure

54 g of 2-chloro-5-trifluoromethyl-1,3-dinitrobenzene are heated to 60° C. together with 64 g of ethylene glycolmonomethyl ether, and 23.5 g of 50 percent strength aqueous sodium hydroxide solution are added dropwise in the course of 30 minutes. The mixture is subsequently stirred at 60° C. for one hour, a further 5 g of sodium hydroxide solution are added and the mixture is subsequently stirred again at 60° C. for a further 1.5 hours. The mixture is then cooled, 50 ml of water are added and the product which has precipitated is filtered off and dried.

Workup

  1. additionare added dropwise in the course of 30 minutes
  2. stirringthe mixture is subsequently stirred again at 60° C. for a further 1.5 hours
  3. temperatureThe mixture is then cooled
  4. customthe product which has precipitated
  5. filtrationis filtered off
  6. customdried

Sources & evidence

ORD record
ord-e38751780aaa48b2a718c790e0ef107f
Source dataset
uspto-grants-1992_01
Patent number
US05078748

Reaction notes

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