1-Amino-2-propanol → HCID 19915461, compound

HRID 1089627Notes

Reaction equation

HRID 1089627 reaction equation
Cl[C:2]1[C:7]([C:8]([F:11])([F:10])[F:9])=[CH:6][C:5]([N+:12]([O-:14])=[O:13])=[CH:4][C:3]=1[N+:15]([O-:17])=[O:16].C([O-])([O-])=O.[Na+].[Na+].[NH2:24][CH2:25][CH:26]([OH:28])[CH3:27]>O>[OH:28][CH:26]([CH3:27])[CH2:25][NH:24][C:2]1[C:7]([C:8]([F:11])([F:10])[F:9])=[CH:6][C:5]([N+:12]([O-:14])=[O:13])=[CH:4][C:3]=1[N+:15]([O-:17])=[O:16]

Participants

5

Reactant 3

HCID 41-Amino-2-propanolHCID 10340Sodium CarbonateHCID 67851Benzene, 2-chloro-1,5-dinitro-3-(trifluoromethyl)-

Product 1

HCID 19915461HCID 19915461, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
80 °C

Procedure

27 g of 4-chloro-5-trifluoromethyl-1,3-dinitrobenzene are initially introduced into 100 ml of water with 5.3 g of Na2CO3, and 13.5 g of 1-aminopropan-2-ol are added at 80° C. in the course of 30 minutes. The mixture is subsequently stirred at 80° C. for one hour and then cooled to room temperature, and the product which has precipitated is filtered off and dried in a vacuum drying cabinet.

Workup

  1. additionare added at 80° C. in the course of 30 minutes
  2. temperaturecooled to room temperature
  3. customthe product which has precipitated
  4. filtrationis filtered off
  5. customdried in a vacuum
  6. customdrying cabinet

Sources & evidence

ORD record
ord-80cea58102594e6c887a010807b17cca
Source dataset
uspto-grants-1992_01
Patent number
US05078748

Reaction notes

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