Dichloromethane → HCID 19071002, compound

HRID 1089630Notes

Reaction equation

HRID 1089630 reaction equation
[O:1]([OH:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:9](Cl)([Cl:11])=[O:10].C(Cl)Cl>CN(C)C=O>[Cl:11][C:9]([O:8][O:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)=[O:10]

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 6371PhosgeneHCID 11051602Phenoxyalcohol

Product 1

HCID 19071002HCID 19071002, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The intermediate phenoxy chloroformates are prepared by reaction of the appropriate phenoxyalcohol with excess phosgene in an inert solvent such as methylene chloride in the presence of a catalytic quantity of dimethyl formamide. The reaction is carried out at 20°-80° C. The solvent and excess phosgene is then removed under vacuo to give the desired intermediate phenoxy chloroformate.

Workup

  1. customis carried out at 20°-80° C
  2. customThe solvent and excess phosgene is then removed under vacuo

Sources & evidence

ORD record
ord-7fbf44ec5be849a481ae3295f6b4bcb1
Source dataset
uspto-grants-1992_01
Patent number
US05078783

Reaction notes

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