Chlorine → HCID 19779379, compound

Participants

Reaction Steps

Chlorine gas was passed through a stirred solution of 4-amino-3-cyanotrifluoromethyl-benzene (5 g) in carbon tetrachloride (75 ml) until the absence of starting material was confirmed by gas liquid chromatography. Flow of the gas was then stopped and evaporation of the solvent under reduced pressure gave 4-amino-3-chloro-5-cyano-trifluoromethyl benzene as an orange solid (5.5 g).

Provenance & Evidence