反应详情

3-Chloroperoxybenzoic acid (0.63 g) was added to a solution of 5'-fluoro-N-methyl-2'-methylsulphinylacetylformanilide (0.78 g), prepared in a similar manner to that described in Example 8, in dichloromethane (25 ml). The mixture was stirred at ambient temperature for 2 hours and then washed with saturated aqueous sodium hydrogen carbonate solution (2×20 ml) and water (2×20 ml). Evaporation in vacuo gave an oil which was crystallised from toluene gave to give 5'-fluoro-N-methyl-2'-methylsulphonylacetylformanilide, m.p. 95°-97° C.

1. customprepared in a similar manner to that
2. washwashed with saturated aqueous sodium hydrogen carbonate solution (2×20 ml) and water (2×20 ml)
3. customEvaporation in vacuo
4. customgave an oil which
5. customwas crystallised from toluene
6. customgave