HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → 4-Methylfluorene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 4-(hydroxymethyl)-9h-fluoren-9-ol | HCID 272052 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 4-Methylfluorene | HCID 15256 | 77.3% |
Reaction Steps
A solution of 9-hydroxyfluoren-4-methanol (2.6 g, 12.2 mmol) in 1.1 EtOAc:AcOH was charged with catalytic amount of 10% palladium on charcoal. The mixture was treated with hydrogen under 1600 psi, at room temperature for three days. The catalyst was removed and the solvent was evaporated under reduced pressure. Recrystalyzation from MeOH afforded 1.7 g (77.0%) of the product as a light yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05079260 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-b24e7e79fc1b4f088fdc4c3c513258a6 |
| Source note | uspto-grants-1992_01 |