HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 1-(2-Carboxy-3-methoxyphenyl)-3-indazolecarboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Indazole-3-carboxylic acid | HCID 78250 | — |
| Reactant | 2-Bromo-6-methoxybenzoic acid | HCID 11117881 | — |
| Catalyst | Copper oxide | HCID 14829 | — |
| Product | 1-(2-Carboxy-3-methoxyphenyl)-3-indazolecarboxylic acid | HCID 19978631 | 36.5% |
Reaction Steps
3-Indazolecarboxylic acid (1.16 g), 0.81 g of 2-bromo-6-methoxybenzoic acid [described in Chem. Ber., 107, 3874 (1974)], 0.79 g of potassium carbonate and 0.04 g of copper(II) oxide were subjected to reaction in the same manner as in Example 1 to obtain 0.40 g (25.6%) of 1-(2-carboxy-3-methoxyphenyl)-3-indazolecarboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05079358 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-fd6a0261d8474e92b2c6ba98351d0ba9 |
| Source note | uspto-grants-1992_01 |