Thionyl Chloride → HCID 14476647, compound

HRID 1089907Notes

Reaction equation

HRID 1089907 reaction equation
[Cl:1][C:2]1[C:7]([C:8]([NH:10][C:11]([CH3:15])([CH3:14])[CH2:12]O)=[O:9])=[CH:6][CH:5]=[CH:4][N:3]=1.S(Cl)([Cl:18])=O>>[Cl:1][C:2]1[C:7]([C:8]([NH:10][C:11]([CH3:15])([CH3:14])[CH2:12][Cl:18])=[O:9])=[CH:6][CH:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 14476646HCID 14476646, compound

Product 1

HCID 14476647HCID 14476647, compound

Procedure

76.8 g (0.336 mole) of 2-chloro 3-(1,1-dimethyl-2-hydroxy-ethyl)aminocarbonyl pyridine are placed in a reaction vessel immersed in a cooling bath (ice+water). 244 ml (3.36 moles) of thionyl chloride are then added so as to maintain the temperature below 20° C.

Workup

  1. customimmersed in a cooling bath
  2. temperatureto maintain the temperature below 20° C.

Sources & evidence

ORD record
ord-40a48724a2094e74ae21538227fd5bec
Source dataset
uspto-grants-1992_01
Patent number
US05079363

Reaction notes

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