Potassium Iodide → HCID 15100876, compound

HRID 1090174Notes

Reaction equation

HRID 1090174 reaction equation
[K].[OH:2][N:3]1[CH:7]=[N:6][CH:5]=[N:4]1.Br[CH:9]([C:13]1[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=1[Cl:20])[CH2:10][CH2:11][CH3:12].[I-].[K+]>CN(C)C=O>[Cl:20][C:14]1[CH:15]=[C:16]([Cl:19])[CH:17]=[CH:18][C:13]=1[CH:9]([O:2][N:3]1[CH:7]=[N:6][CH:5]=[N:4]1)[CH2:10][CH2:11][CH3:12]

Participants

6

Reactant 4

HCID 4875Potassium IodideHCID 5462222PotassiumHCID 14670780HCID 14670780, compoundHCID 15100875HCID 15100875, compound

Product 1

HCID 15100876HCID 15100876, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent2×

Procedure

1.2 g (10 mmol) of the potassium salt of 1-hydroxy-1,2,4-triazole were dissolved in 100 ml of dimethylformamide and the solution was added at room temperature to a solution of 4.0 g (10 mmol) of 1-bromo-1-(2,4-dichlorophenyl)-butane in 50 ml of dimethylformamide. 0.1 g of potassium iodide was added to the mixture, which was refluxed for 10 minutes. Thereafter, the solvent was removed under reduced pressure, the residue was taken up in ether and the solution was washed three times with water. After the organic phase had been dried with Na2SO4, the solvent was removed under reduced pressure.

Workup

  1. temperaturewas refluxed for 10 minutes
  2. customThereafter, the solvent was removed under reduced pressure
  3. washthe solution was washed three times with water
  4. dry with materialAfter the organic phase had been dried with Na2SO4
  5. customthe solvent was removed under reduced pressure

Sources & evidence

ORD record
ord-bf72046bb3b34ebc86ac0791b36b5b6e
Source dataset
uspto-grants-1992_01
Patent number
US05081142

Reaction notes

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