HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 13376629, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Methyl α-(4-chlorophenyl)-1H-1,2,4-triazole-1-propanoate | HCID 19914727 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 13376629 | HCID 13376629 | — |
Reaction Steps
1.3 g of LiAlH4 is suspended in 170 ml of anhydrous diethyl ether under N2 atmosphere. Within one hour, 8 g of methyl α-(1H-1,2,4-triazol-1-ylmethyl)-4-chlorophenylacetate is introduced. The reaction is exothermic, and proceeds with solvent reflux. At the end of heat evolution, 10 ml of methanol in 50 ml of diethyl ether is added to destroy the excess of hydride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05081141 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-4bd18d60daf348ec8a77c05eef8b5ed5 |
| Source note | uspto-grants-1992_01 |